Article
Murine Immunoglobulin G Subclass Responses Following Immunization with Live Dengue Virus or a Recombinant Dengue Envelope Protein
1 Oct 1995
Abstract excerpt
Murine immunoglobulin G (IgG) subclass responses to immunization are restricted to certain subclasses depending on the nature of the immunogen. Immunization with live viruses generally leads to a predominant IgG2a response, which may be the most effective at resisting future challenge due to the unique effector functions of IgG2a. Knowledge of subclass responses following immunization with dengue vaccine...
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