Article
Dengue Vaccines: The Promise and Pitfalls of Antibody-Mediated Protection.
Cell host & microbe - 13 Jan 2021
Martinez David R, Metz Stefan W, Baric Ralph S
Abstract excerpt
More than 390 million human dengue virus (DENV) infections occur each year, worldwide. Dengvaxia, a live-virus tetravalent vaccine from Sanofi Pasteur, was recently approved for human clinical use, although vaccine performance against the four DENV serotypes is highly variable. Other dengue vaccines in advanced clinical testing also demonstrate variability in efficacy. In this review, we outline the benefits and...
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