Heparin-induced thrombocytopenia and fatal thrombosis in a patient with activated protein C resistance.

doi:10.1002/ajh.2830500412

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Article

Heparin-induced thrombocytopenia and fatal thrombosis in a patient with activated protein C resistance.

American journal of hematology - 1 Dec 1995

Gardyn J, Sorkin P, Kluger Y, Kabili S, Klausner J M, Zivelin A, Eldor A

Abstract excerpt

We report a 20-year-old woman who developed heparin-induced thrombocytopenia (HIT) associated with devastating and fatal multiorgan thrombosis. The patient, her mother, and her brother were found to have resistance to activated protein C (APC), and the congenital thrombophilia in this family was...

Topics

Adult
Base Sequence
Colectomy
DNA
Drug Resistance
Factor V
Fatal Outcome
Female
Heparin
Humans
Ileostomy
Mesenteric Arteries
Molecular Sequence Data
Mutation
Protein C
Thrombocytopenia
Thrombosis

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