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Article

Y chromosome short arm-Sxr recombination in XSxr/Y males causes deletion of Rbm and XY female sex reversal.

Proceedings of the National Academy of Sciences of the United States of America - 24 Oct 1995

Laval S H, Glenister P H, Rasberry C, Thornton C E, Mahadevaiah S K, Cooke H J, Burgoyne P S, Cattanach B M

Abstract excerpt

We earlier described three lines of sex-reversed XY female mice deleted for sequences believed close to the testes-determining gene (Sry) on the Y chromosome short arm (Yp). The original sex-reversed females appeared among the offspring of XY males that carried the Yp duplication Sxr on their X chromosome. Earlier cytogenetic observations had suggested that the deletions resulted from asymmetrical meiotic...

Topics

Animals
Base Sequence
Biological Evolution
Blotting, Southern
Chromosome Mapping
DNA Primers
DNA-Binding Proteins
Disorders of Sex Development
Female
Gene Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Carrier Screening

Genetic Variation

Humans

Hypoxanthine Phosphoribosyltransferase

Male

Mice

Mice, Inbred AKR

Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 7479793
DOI: 10.1073/pnas.92.22.10403
PMCID: PMC40805

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7479793-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Y chromosome short arm-Sxr recombination in XSxr/Y males causes deletion of Rbm and XY female sex reversal.PMID 7479793Read ↗

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