Article
Dosage compensation of the Drosophila white gene requires both the X chromosome environment and multiple intragenic elements.
Genetics - 1 Feb 1995
Qian S, Pirrotta V
Abstract excerpt
The X-linked white gene when transposed to autosomes retains only partial dosage compensation. One copy of the gene in males expresses more than one copy but less than two copies in females. When inserted in ectopic X chromosome sites, the mini-white gene of the CaspeR vector can be fully dosage compensated and can even achieve hyperdosage compensation, meaning that one copy in males gives more expression than...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
