Aberrant splicing and transcription termination caused by P element insertion into the intron of a Drosophila gene.

doi:10.1093/genetics/139.1.327

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Article

Aberrant splicing and transcription termination caused by P element insertion into the intron of a Drosophila gene.

Genetics - 1 Jan 1995

Horowitz H, Berg C A

Abstract excerpt

Insertional mutagenesis screens using the P[lacZ, rosy+] (PZ) transposable element have provided thousands of mutant lines for analyzing genes of varied function in the fruitfly, Drosophila melanogaster. As have been observed with other P elements, many of the PZ-induced mutations result from insertion of the P element into the promoter or 5' untranslated regions of the affected gene. We document here a novel...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Crosses, Genetic
Drosophila melanogaster
Female
Genes, Insect
Introns
Male
Molecular Sequence Data
Mutagenesis, Insertional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nucleic Acid Hybridization

Polymerase Chain Reaction

Proteins

RNA Splicing

RNA, Messenger

Recombinant Fusion Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 7705633
DOI: 10.1093/genetics/139.1.327
PMCID: PMC1206329

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7705633-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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