The association of combined alpha and beta fibrinogen genotype on plasma fibrinogen levels in smokers and non-smokers.

doi:10.1136/jmg.32.8.585

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Article

The association of combined alpha and beta fibrinogen genotype on plasma fibrinogen levels in smokers and non-smokers.

Journal of medical genetics - 1 Aug 1995

Thomas A E, Green F R, Lamlum H, Humphries S E

Abstract excerpt

OBJECTIVE: To determine in healthy men: (1) whether an extended genotype of the fibrinogen gene cluster using the G/A-455 and the BclI polymorphism of the beta fibrinogen gene and TaqI of the alpha fibrinogen gene explains a significantly larger proportion of variance in plasma fibrinogen levels...

Topics

Alleles
Fibrinogen
Genetic Variation
Genotype
Humans
Linkage Disequilibrium
Male
Multigene Family
Polymorphism, Genetic
Reference Values
Regression Analysis
Restriction Mapping
Smoking

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