Article
Gender-related association between beta-fibrinogen genotype and plasma fibrinogen levels and linkage disequilibrium at the fibrinogen locus in Greenland Inuit.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 1995
de Maat M P, de Knijff P, Green F R, Thomas A E, Jespersen J, Kluft C
Abstract excerpt
Elevated plasma fibrinogen levels represent an increased risk for cardiovascular disease, but the mechanism explaining this association is still not clear. Genetic differences may play a role, because it has been shown that individuals who carry the rare alleles of polymorphisms in the genes for...
Topics
- Adult
- Alleles
- Asian People
- Body Mass Index
- C-Reactive Protein
- Deoxyribonucleases, Type II Site-Specific
- Female
- Fibrinogen
- Genotype
- Greenland
- Humans
- Inuit
- Linkage Disequilibrium
- Male
- Polymorphism, Restriction Fragment Length
- Sex Characteristics
- Smoking