Article
Increase of HLA haplotype A9-Bw16 in familial insulin-dependent diabetes mellitus in northern-Finland.
Acta diabetologica latina - 1 Jan 2000
Ilonen J, Akerblom H K, Tiilikainen A, Mustonen A, Herva E, Koskimies S, Kouvalainen K
Abstract excerpt
Twenty-one families, each with two diabetic children, from North Finland were HLA typed. The grade of HLA identity between diabetic siblings was evaluated, and frequencies of various HLA antigens in familial cases were compared to those of non-familial cases from the same area. Ten pairs of diabetic children were HLA-identical and eleven haploidentical; two of the latter were identical for the HLA-D locus. These...
Topics
- Diabetes Mellitus
- Finland
- Gene Frequency
- HLA Antigens
- Humans
- Insulin
- Phenotype
