Structure of the fibers of hemoglobin S.

Abstract excerpt

Several lines of evidence are converging on a consistent model for the structure of the fibers of hemoglobin S. The basic structure of the fibers is a solid helical assembly of 14 protofilaments deduced from three-dimensional reconstructions of electron micrographs. The filaments are organized in half-staggered pairs which appear to be related to the pairs of filaments in a crystal form of hemoglobin S studied by...

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