Article
Cytogenetic analysis of an immunogenic mutant of the L5178Y lymphoma.
Acta cytologica - 1 Jan 2000
Greenberg A H, Manougian J, Ray M, Goldenberg G J
Abstract excerpt
A mutant of the uniformly lethal L5178Y lymphoma, called the L5178Y/Manitoba (L5178Y/M), was rejected after subcutaneous challenge in syngeneic DBA/2 mice. Karyotypic analysis revealed that the parent L5178Y lymphoma had four chromosome markers, with the mutant L5178Y/M sharing one of them as well as possessing two distinguishing markers. One diploid and two hypotetraploid clones were isolated from the L5178Y/M;...
Topics
- Animals
- Clone Cells
- Cross Reactions
- Female
- Genetic Markers
- Graft Rejection
- Karyotyping
- Leukemia L5178
- Leukemia, Experimental
- Lymphoma
- Male
- Mast-Cell Sarcoma