Article
Tumor antigens.
Annual review of immunology - 1 Jan 1992
Urban J L, Schreiber H
Abstract excerpt
This review solidifies a new concept that common and rare types of human cancers harbor a variety of tumor-specific mutant proteins that may be recognized as tumor-specific antigens. These mutant proteins are encoded by oncogenes or suppressor genes that have undergone structural mutations resulting from point mutations, chromosomal translocations, internal deletions and viral insertional mutagenesis; several of...
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