Screening mouse mutations for resistance to cancer metastasis.

doi:10.1007/BF00215051

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Article

Screening mouse mutations for resistance to cancer metastasis.

Immunogenetics - 1 Jan 1992

Egorov O S, Liu Y, Sargent E E, Drizlikh G I, Egorov I K

Abstract excerpt

To search for host genes for resistance/susceptibility to cancer metastasis, mutation analysis was employed. Ten putative mutants of resistance to lymphoma EL4 and four putative mutants of resistance to sarcoma MCA/77-23 of C57BL/6J (B6) mice were produced. These mutants were designated S (for "s...

Topics

Animals
Crosses, Genetic
Female
Genetic Linkage
Genetic Predisposition to Disease
H-2 Antigens
Lymphoma
Male
Mice
Mice, Inbred C57BL
Mutation
Neoplasm Metastasis
Neoplasm Transplantation
Rhabdomyosarcoma
Sarcoma, Experimental

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