Article
Analysis of linkage and association for diseases of genetic aetiology.
Statistics in medicine - 1 Jan 2000
Sturt E
Abstract excerpt
This presentation attempts to clarify certain caveats that apply to the use of linkage analysis when the genetics of one of the characters is not completely known. The effects of linkage and association can be difficult to distinguish both within pedigrees and across the general population. Linkage analysis methods are not robust to departures from the assumptions of the model. These assumptions do not allow for...
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