Article
Persistent infection with an influenza C virus variant is dominantly established in the presence of the parental wild-type virus.
Virus research - 1 Mar 1998
Marschall M, Helten A, Hechtfischer A, Zach A, Meier-Ewert H
Abstract excerpt
Two influenza C viruses were used for double-infection experiments to investigate the dominance of their phenotypes. The wild-type virus (C/AA-wt) had been characterized by its short-lived productive cycle, whereas a distinct variant derived from it (C/AA-pi) was demonstrated to persist in long-term passages of infected MDCK cultures. Here we show that the persistent virus C/AA-pi is capable of replicating in the...
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