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Article

Ah receptor antagonism represses head and neck tumor cell aggressive phenotype.

Molecular cancer research : MCR - 1 Oct 2012

DiNatale Brett C, Smith Kayla, John Kaarthik, Krishnegowda Gowdahalli, Amin Shantu G, Perdew Gary H

Abstract excerpt

The aryl hydrocarbon receptor (AhR) has been shown to play a role in an increasing number of cellular processes. Recent reports have linked the AhR to cell proliferation, cytoskeletal arrangement, and tumor invasiveness in various tumor cell types. The AhR plays a role in the de-repression of the interleukin (IL)6 promoter in certain tumor cell lines, allowing for increased transcriptional activation by...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
Share to Head and Neck Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22912337
DOI: 10.1158/1541-7786.MCR-12-0216
PMCID: PMC3477495

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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