Article
Information for the dorsal--ventral pattern of the Drosophila embryo is stored as maternal mRNA.
Nature - 1 Jan 2000
Anderson K V, Nüsslein-Volhard C
Abstract excerpt
Maternal-effect mutations in 10 loci in Drosophila produce totally 'dorsalized' embryos. Injection of RNA isolated from wild-type embryos into mutants at six loci partially restores dorsal-ventral polarity. For the mutant snake, injection of poly(A)+ RNA restores a complete dorsal-ventral pattern.
Topics
- Animals
- Drosophila melanogaster
- Morphogenesis
- Phenotype
- RNA, Messenger
