Article
cactus, a maternal gene required for proper formation of the dorsoventral morphogen gradient in Drosophila embryos.
Development (Cambridge, England) - 1 Jun 1991
Roth S, Hiromi Y, Godt D, Nüsslein-Volhard C
Abstract excerpt
The dorsoventral pattern of the Drosophila embryo is mediated by a gradient of nuclear localization of the dorsal protein which acts as a morphogen. Establishment of the nuclear concentration gradient of dorsal protein requires the activities of the 10 maternal 'dorsal group' genes whose function results in the positive regulation of the nuclear uptake of the dorsal protein. Here we show that in contrast to the...
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