Article
An in vivo assay of the mutagenic potential of imidacloprid using sperm head abnormality test and dominant lethal test.
Drug and chemical toxicology - 1 Jan 2015
Bagri Preeti, Kumar Vinod, Sikka Anil Kumar
Abstract excerpt
OBJECTIVE: To assess the mutagenic effects of imidacloprid in germ cells of Swiss albino male mice by sperm head abnormality (SHA) assay and dominant lethal test (DLT). METHODS: Swiss albino mice were exposed to imidacloprid (22, 11 and 5.5 mg/kg/day) along with 3% gum acacia as vehicle control through oral route for 7, 14 and 28 days for SHA assay and for 28 days for DLT. The epididymal sperm smear in 1% eosin...
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