Investigations on the in vitro and in vivo genotoxic potential of 5-vinyl-2-norbornene.

doi:10.1002/(sici)1099-1263(199803/04)18:2<129::aid-jat484>3.0.co;2-c

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Article

Investigations on the in vitro and in vivo genotoxic potential of 5-vinyl-2-norbornene.

Journal of applied toxicology : JAT - 1 Jan 2000

Vergnes J S, Ballantyne B

Abstract excerpt

5-Vinyl-2-norbornene (VNB: CAS no. 3048-64-4), an industrial chemical that produces hyaline droplet nephropathy in the male rat with associated alpha2u-globulin increases, was investigated in vitro and in vivo for its genotoxic potential. A Salmonella typhimurium reverse mutation assay (strains T...

Topics

Animals
CHO Cells
Chromosome Aberrations
Cricetinae
Dose-Response Relationship, Drug
In Vitro Techniques
Male
Mutagenicity Tests
Mutation
Norbornanes
Rats
Salmonella typhimurium
Sister Chromatid Exchange

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