Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigations on the in vitro and in vivo genotoxic potential of 5-vinyl-2-norbornene.

Journal of applied toxicology : JAT - 1 Jan 2000

Vergnes J S, Ballantyne B

Abstract excerpt

5-Vinyl-2-norbornene (VNB: CAS no. 3048-64-4), an industrial chemical that produces hyaline droplet nephropathy in the male rat with associated alpha2u-globulin increases, was investigated in vitro and in vivo for its genotoxic potential. A Salmonella typhimurium reverse mutation assay (strains TA98, 100, 1535, 1537, 1538) was negative both without (dose range 0.003-0.3 mg per plate) and with (0.003-0.3 mg per...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CHO Cells
Share to Chromosome Aberrations
Share to Cricetinae

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Drug

Share to In Vitro Techniques

Share to Mutation

Share to Salmonella typhimurium

Source

Identifiers

PMID: 9570696
DOI: 10.1002/(sici)1099-1263(199803/04)18:2<129::aid-jat484>3.0.co;2-c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigations on the in vitro and in vivo genotoxic potential of 5-vinyl-2-norbornene.PMID 9570696Read ↗

Genetic Toxicity Studies of the Ketogenic Ester Bis Hexanoyl (R)-1,3-Butanediol.Semantic proximity Read ↗

In vivo pig-a and micronucleus study of the prototypical aneugen vinblastine sulfate.Semantic proximity Read ↗

Evaluation of genotoxicity of N-nitrosodibenzylamine in Chinese hamster V79 cells and in Salmonella.Semantic proximity Read ↗

Evaluation of genotoxicity of multi-walled carbon nanotubes in a battery of in vitro and in vivo assays.Semantic proximity Read ↗

Mutagenicity of vinyl chloride monomer.Semantic proximity Read ↗

Mutagenicity of vinyl chloride and its reactive metabolites, chloroethylene oxide and chloroacetaldehyde, in a metabolically competent human B-lymphoblastoid line.Semantic proximity Read ↗

Characterization by two-endpoint comparisons of the genetic toxicity profiles of vinyl chloride and related etheno-adduct forming carcinogens in Drosophila.Semantic proximity Read ↗

Nonlinear responses for chromosome and gene level effects induced by vinyl acetate monomer and its metabolite, acetaldehyde in TK6 cells.Semantic proximity Read ↗

Genotoxicity assessment of melamine in the in vivo Pig-a mutation assay and in a standard battery of assays.Semantic proximity Read ↗

Genetic toxicity of the benzene metabolite trans, trans-muconaldehyde in mammalian and bacterial cells.Semantic proximity Read ↗

Genotoxicity assessment of an energetic propellant compound, 3-nitro-1,2,4-triazol-5-one (NTO).Semantic proximity Read ↗

Genotoxicity of vanadium compounds in yeast and cultured mammalian cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.