Article
Review of the mutagenicity of ethylene oxide.
Environmental and molecular mutagenesis - 1 Jan 1990
Dellarco V L, Generoso W M, Sega G A, Fowle J R, Jacobson-Kram D
Abstract excerpt
Ethylene oxide has been shown to be an effective mutagen in a variety of organisms ranging from bacteria to mammalian cells. There is also an association between ethylene oxide exposure and human somatic cell cytogenetic damage. Furthermore, ethylene oxide has been shown to alkylate protein and DNA at exposure levels that have been encountered occupationally. Ethylene oxide is not only effective at producing...
Topics
- Animals
- Ethylene Oxide
- Germ Cells
- Humans
- Mutagens
- Mutation
- Risk Factors
- Sister Chromatid Exchange