Article
Embryo toxicity and teratogenicity of formaldehyde.
Archives of environmental health - 1 Jan 2000
Thrasher J D, Kilburn K H
Abstract excerpt
C-14 formaldehyde crosses the placenta and enters fetal tissues. The incorporated radioactivity is higher in fetal organs (i.e., brain and liver) than in maternal tissues. The incorporation mechanism has not been studied fully, but formaldehyde enters the single-carbon cycle and is incorporated as a methyl group into nucleic acids and proteins. Also, formaldehyde reacts chemically with organic compounds (e.g.,...
Topics
- Animals
- Chromosome Deletion
- Disease Models, Animal
- Embryo, Mammalian
- Environmental Exposure
- Environmental Monitoring
- Female
- Formaldehyde
- Gestational Age
- Humans
- Maternal-Fetal Exchange
- Maximum Allowable Concentration