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Genotoxicity of flubendazole and its metabolitesin vitroand the impact of a new formulation onin vivoaneugenicity

6 Oct 2015

Abstract excerpt

The anti-parasitic benzimidazole flubendazole has been used for many years to treat intestinal infections in humans and animals. Previous genotoxicity studies have shown that the compound is not a bacterial mutagen and a bone marrow micronucleus test, using a formulation that limited systemic absorption, was negative. The purpose of this study is to explore the genotoxicity of flubendazole and its main...

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PMID: 26443851
DOI: 10.1093/mutage/gev070

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