Frequency of spontaneous and induced "point" mutations in higher eukaryotes.

Abstract excerpt

Data are presented on comparative mutation rates in Drosophila, mice, and humans, as derived from the study of both biochemical and morphological traits. There is a notable similarity in these rates, despite the large differences in average generation time, mean body temperature, and number of cell divisions intervening between fertilization of the egg and production of functional gametes. This suggests the...

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