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De novo mutations in domestic cat are consistent with an effect of reproductive longevity on both the rate and spectrum of mutations

2021-04-06

Abstract excerpt

The mutation rate is a fundamental evolutionary parameter with direct and appreciable effects on the health and function of individuals. Here, we examine this important parameter in the domestic cat, a beloved companion animal as well as a valuable biomedical model. We estimate a mutation rate of 0.86 × 10 -8 per bp per generation for the domestic cat (at an average parental age of 3.8 years). We find evidence fo...

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Literature Corpus work: f2187424-3185-5ab5-b217-f032e4b73cfe
DOI: 10.1101/2021.04.06.438608

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De novo mutations in domestic cat are consistent with an effect of reproductive longevity on both the rate and spectrum of mutationsDOI 10.1101/2021.04.06.438608Read

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<i>De novo</i> mutations in domestic cat are consistent with an effect of reproductive longevity on both the rate and spectrum of mutations

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