Article
Effect of altered lipid A synthesis on the synthesis of major proteins of the Salmonella typhimurium outer membrane.
Reviews of infectious diseases - 1 Jan 2000
Rick P D, Neumeyer B A, Young D A
Abstract excerpt
The effect of altered lipid A synthesis on the synthesis of major outer membrane proteins was investigated in mutants of Salmonella typhimurium conditionally defective in the synthesis of 3-deoxy-D-mannooctulosonic acid (KDO). The defect is due to a mutation in the structural gene for KDO-8-phosphate synthetase (designated kdsA), and expression of this lesion results in the accumulation of a precursor of lipid A...
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