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Article

Transcriptional interference in avian retroviruses--implications for the promoter insertion model of leukaemogenesis.

Nature - 1 Jan 2000

Cullen B R, Lomedico P T, Ju G

Abstract excerpt

The downstream (3') long terminal repeat (LTR) of an avian retroviral provirus is unable to act as an efficient promoter of transcription when a transcriptionally active upstream (5') LTR is present. This transcriptional interference may explain the observation that only deleted proviruses have been observed inserted adjacent to c-myc in avian leukosis virus induced lymphomas of chickens.

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Identifiers

PMID: 6363938
DOI: 10.1038/307241a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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