Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of HLA-DR antigens at the surface of mouse L cells co-transfected with cloned human genes.

Nature - 1 Jan 2000

Rabourdin-Combe C, Mach B

Abstract excerpt

The H-2 I region in the mouse and the HLA-D region in humans contain a set of polymorphic genes which encode Ia antigens and control the immune response. Cloned genes for the different polypeptide chains of one of the human Ia antigens, HLA-DR, have been used for the co-transformation of mouse L cells. Expression of HLA-DR antigens at the surface of transfected mouse cells has been documented with monoclonal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cloning, Molecular
Share to Fluorescent Antibody Technique
Share to Genes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-DR Antigens

Share to Mutation

Share to Nucleic Acid Hybridization

Share to Transfection

Source

Identifiers

PMID: 6304534
DOI: 10.1038/303670a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Expression of HLA-DR antigens at the surface of mouse L cells co-transfected with cloned human genes.PMID 6304534Read ↗

Hybrid HLA-DC antigens provide molecular evidence for gene trans-complementation.Semantic proximity Read ↗

Characterization and epitope mapping of four HLA class II reactive mouse monoclonal antibodies using transfected L cells and human cells transfected with mutants of DQB1*0302.Semantic proximity Read ↗

Expression of CD44 confers a new adhesive phenotype on transfected cells.Semantic proximity Read ↗

Expression of HLA class I molecules assembled with structural variants of human beta2-microglobulin.Semantic proximity Read ↗

Cell surface expression of hybrid murine/human MHC class II beta alpha dimers. Key influence of residues in the amino-terminal portion of the beta 1 domain.Semantic proximity Read ↗

Production and characterization of murine monoclonal antibodies recognizing HLA-DQ polymorphisms obtained by immunizing mice with transfected L cells.Semantic proximity Read ↗

HLA class II transgenic mice as models of human diseasesSemantic proximity Read ↗

Human MHC Class I-restricted high avidity CD4 + T cells generated by co-transfer of TCR and CD8 mediate efficient tumor rejection in vivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.