Article
RH locus contraction in a novel Dc-/D-- genotype resulting from separate genetic recombination events.
Transfusion - 1 Jun 2004
Huang C-H, Peng J, Chen H C, Chen Y X, Lin D-T, Lin S W-S, Reid M E, Powell V I
Abstract excerpt
BACKGROUND: The rare phenotypes Dc- and D-- lack the expression of E/e and CcEe antigens, respectively; their cotransmission in a single family has not been reported. STUDY DESIGN AND METHODS: Six members of a Chinese family with two exhibiting the Dc- phenotype were studied using standard serologic methods. Rh genotypes were analyzed by Southern blot, and RH loci, by exon PCR. Rh transcripts were characterized...
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