Article
High-density lipoprotein, low-density lipoprotein and triglyceride levels and upper gastrointestinal cancers risk: a trans-ancestry Mendelian randomization study.
European journal of clinical nutrition - 1 Jul 2022
Wu Yanling, Xin Junyi, Loehrer Elizabeth A, Jiang Xia, Yuan Qianyu, Christiani David C, Shi Hanping, Liu Lingxiang, Li Shuwei, Wang Meilin, Chu Haiyan, Du Mulong, Zhang Zhengdong
Abstract excerpt
OBJECTIVE: This study was conducted to explore the causal associations of high-density lipoprotein (HDL), low-density lipoprotein (LDL) and triglyceride (TG) with the risk of upper gastrointestinal cancers (esophageal cancer [EC] and gastric cancer [GC]). METHODS: A total of 5623 Chinese and 4133 Europeans afforded the individual-level genotyping data, and 203,608 Japanese from Biobank Japan project and 393,926...
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