Article
Myeloid Dendritic Cell Counts and Coronary Heart Disease: a Bidirectional Mendelian Randomization Study.
Clinical laboratory - 1 Sept 2026
Lv Feng, Zhou Lihong, Pan Rongrong, Zhang Ting, Jiang Yufeng, Zhang Junyi, Zhou Yafeng
Abstract excerpt
BACKGROUND: Coronary heart disease (CHD) remains a leading cause of morbidity and mortality worldwide, with immune and inflammatory mechanisms playing important roles in its pathogenesis. Dendritic cells (DCs) are key regulators of immune responses; however, the relationship between specific DC subsets and CHD risk remains incompletely understood. METHODS: This study conducted a bidirectional two-sample Mendelian...
Read the complete abstract on PubMedTopics
- Humans
- Dendritic Cells
- Mendelian Randomization Analysis
- Genome-Wide Association Study
- Coronary Disease
- Genetic Predisposition to Disease
