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Article

Causal Mediation of Immune Cells and Fatty Acids in Coronary Atherosclerosis: Insights From Mendelian Randomization Analysis.

Human mutation - 1 Jan 2026

Zhang Yong, Xu Jia, Deng Zhihao, Long Xiang, Liu Jukun, Jiang Linhui, Liu Nanbo, Zhang Dengfeng, Zhou Wenkai, Zhu Ping

Abstract excerpt

Observational studies have suggested a link between total fatty acid levels and the development of coronary atherosclerosis. While the involvement of immune cells in the pathogenesis of this condition is well-established, the precise causal mechanisms by which fatty acids influence immune cell function and subsequently affect coronary atherosclerosis remain unclear. To address this, we systematically assessed the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42181739
DOI: 10.1155/humu/1253577
PMCID: PMC13197653

Genes

CD86

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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