Causal relationships between blood cell perturbation responses, immune cell phenotypes, and cardiomyopathy: A two-sample Mendelian randomization and mediation analysis.

Abstract excerpt

Clinical investigations have demonstrated that blood and immune cells are involved in the pathophysiological processes of dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM). However, the causal relationships between these cellular components and the development of DCM and HCM remain uncertain. A two-sample Mendelian randomization analysis was performed to evaluate the causal effects of blood cells...

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• Blood Cells
• Cardiomyopathies
• Cardiomyopathy, Dilated
• Cardiomyopathy, Hypertrophic
• Mendelian Randomization Analysis