Immune cells and rheumatic heart disease: A 2-sample and Bayesian weighted Mendelian randomization study.

Abstract excerpt

Using Mendelian randomization (MR) analysis to explore the immune cells involved in rheumatic heart disease (RHD). We conducted a bidirectional 2-sample MR study to screen the causal effects of 731 immune cell phenotypes on RHD. MR analysis was performed using regression models including inverse variance weighting, MR-Egger method, simple mode method, weighted median method, and weighted mode method. At the same...

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• Bayes Theorem
• CD14 gene
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Mendelian Randomization Analysis