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Article

Assessing the Effects of Childhood and Adult Body Mass Index on Diabetic Retinopathy Risk: A Mendelian Randomization Study.

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2026

Gao Luxia, Guo Siyu, Zhu Wengen, Zhou Yue

Abstract excerpt

OBJECTIVE: Obesity is linked to Diabetic Retinopathy (DR), but the relationship between childhood obesity and DR remains unclear. This study uses Mendelian Randomization (MR) to investigate this link. METHODS: Univariate MR assessed the associations between childhood and adult Body Mass Index (BMI) and DR risk, followed by multivariable MR to distinguish their specific effects. Summary data were obtained from the...

Read the complete abstract on PubMed

Topics

Humans
Mendelian Randomization Analysis
Body Mass Index
Diabetic Retinopathy
Child
Risk Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Pediatric Obesity

Adult

Male

Female

Genetic Predisposition to Disease

Age Factors

Source

Identifiers

PMID: 42725617
DOI: 10.2174/0118715303487103260827072037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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