Article
Mendelian randomization analysis of the association between childhood overweight or obesity and gestational diabetes mellitus.
Diabetes, obesity & metabolism - 1 Dec 2024
Jiang Huaiyan, Zhang Kun, Zhang Xi
Abstract excerpt
OBJECTIVE: To investigate the association between childhood overweight or obesity and gestational diabetes mellitus (GDM). METHODS: Data were sourced from the Genome-Wide Association Studies database on childhood body mass index (BMI), with 39 620 samples and 8 173 382 single-nucleotide polymorphisms (SNPs), and GDM, with 143 441 samples, including 12 332 GDM cases and 20 149 608 SNPs. Mendelian randomization...
Topics
- Humans
- Diabetes, Gestational
- Female
- Mendelian Randomization Analysis
- Pregnancy
- Polymorphism, Single Nucleotide
- Pediatric Obesity
- Body Mass Index
- Genome-Wide Association Study
- Child
- Risk Factors
