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Article

[State Changes and Stability Grading of Driver Genes in Non-small Cell Lung Cancer Based on Repeated NGS Testing].

Zhongguo fei ai za zhi = Chinese journal of lung cancer - 20 Jul 2026

Zhao Dan, Xu Fudong, Zhang Lili, Zhang Nana, Liu Zichen, Li Kun, Zhang Chen, Zhou Lijuan, Dong Yujie, Mu Jing, Che Nanying

Abstract excerpt

BACKGROUND: Next-generation sequencing (NGS)-based driver gene testing has become a routine component of molecular subtyping and precision therapy for non-small cell lung cancer (NSCLC). Dynamic genomic monitoring facilitates early detection of resistance-related molecular alterations and informs timely therapeutic adjustments. However, standardized criteria for evaluating the stability of serial NGS testing are...

Read the complete abstract on PubMed

Topics

Humans
Lung Neoplasms
Carcinoma, Non-Small-Cell Lung
Male
Proto-Oncogene Mas
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Middle Aged

Aged

Mutation

Retrospective Studies

Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 42705851
DOI: 10.3779/j.issn.1009-3419.2026.106.18
PMCID: PMC13559061

Genes

PIK3CA
MET
ALK
BRAF
ROS1
EGFR
ERBB2
KRAS
RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 26 Oct 2026.

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