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Nationwide data from comprehensive genomic profiling assays for detecting driver oncogenes in non-small cell lung cancer.

Cancer science - 1 May 2024

Ishida Masaki, Iwasaku Masahiro, Doi Toshifumi, Ishikawa Takeshi, Tachibana Yusuke, Sawada Ryo, Ogura Yuri, Kawachi Hayato, Katayama Yuki, Nishioka Naoya, Morimoto Kenji, Tokuda Shinsaku, Yamada Tadaaki, Takayama Koichi

Abstract excerpt

Driver oncogenes are investigated upfront at diagnosis using multi-CDx systems with next-generation sequencing techniques or multiplex reverse-transcriptase polymerase chain reaction assays. Additionally, from 2019, comprehensive genomic profiling (CGP) assays have been available in Japan for patients with advanced solid tumors who had completed or were expected to complete standard chemotherapy. These assays are...

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Identifiers

PMID: 38450844
DOI: 10.1111/cas.16130
PMCID: PMC11093184

Genes

EGFR
ALK
BRAF
KRAS
ROS1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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