Association between human leukocyte antigen-DQ2/DQ8 positivity and incident atrial fibrillation in patients with heart failure with reduced ejection fraction.

doi:10.1590/1806-9282.20260404

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Article

Association between human leukocyte antigen-DQ2/DQ8 positivity and incident atrial fibrillation in patients with heart failure with reduced ejection fraction.

Revista da Associacao Medica Brasileira (1992) - 1 Jan 2026

Küçük Uğur, Akşit Ercan

Abstract excerpt

OBJECTIVE: Genetic susceptibility is increasingly recognized in cardiac arrhythmias. human leukocyte antigen-DQ2 and human leukocyte antigen-DQ8 alleles are established markers of immune-genetic dysregulation and chronic inflammation. This study investigated the association between human leukocyte antigen-DQ2/DQ8 positivity and incident atrial fibrillation in patients with heart failure with reduced ejection...

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Topics

Humans
Atrial Fibrillation
Heart Failure
Female
HLA-DQ Antigens
Male
Stroke Volume

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Genetic Predisposition to Disease

Aged

Case-Control Studies

Retrospective Studies

Risk Factors

Incidence

Source

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Identifiers

PMID: 42690360
DOI: 10.1590/1806-9282.20260404
PMCID: PMC13502740

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