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Article

Genetic Factors Altering Immune Responses in Atrial Fibrillation: JACC Review Topic of the Week.

Journal of the American College of Cardiology - 26 Mar 2024

Ninni Sandro, Dombrowicz David, de Winther Menno, Staels Bart, Montaigne David, Nattel Stanley

Abstract excerpt

Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide and is associated with a range of adverse clinical outcomes. Accumulating evidence points to inflammatory processes resulting from innate immune responses as a cornerstone in AF pathogenesis. Genetic and epigenetic factors affecting leukocytes have been identified as key modulators of the inflammatory response. Inherited variants in genes...

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Identifiers

PMID: 38508850
DOI: 10.1016/j.jacc.2023.12.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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