Mapping the modifiable exposome for ischemic stroke: association, causality, and preventive potential.

doi:10.1016/j.atherosclerosis.2026.120693

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Article

Mapping the modifiable exposome for ischemic stroke: association, causality, and preventive potential.

Atherosclerosis - 1 Sept 2026

Zheng Manqi, Xu Qin, Xia Xue, Gao Meng, Li Jing, Huang Xiaoyan, Wang Anxin

Abstract excerpt

BACKGROUND AND AIMS: Previous hypothesis-driven studies focused on limited risk factors for ischemic stroke (IS) with inconsistent findings. We aimed to systematically identify modifiable factors, assess causality, quantify joint impact, and evaluate public health implications of conservative versus radical multi-domain IS intervention strategies. METHODS: We conducted a large prospective cohort study using UK...

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PMID: 42660570
DOI: 10.1016/j.atherosclerosis.2026.120693

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