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Article

Mapping the causal landscape of polycystic ovary syndrome: A systematic Mendelian randomization evidence synthesis and the MR-PCOS atlas platform.

Medicine - 21 Aug 2026

Du Sanwei, Dai Dandan, Pan Wenhao, Zhou Junlin, Wang Kexin

Abstract excerpt

Mendelian randomization (MR) studies have increasingly investigated potential predicted antecedents and consequences of polycystic ovary syndrome (PCOS), yet published evidence remains scattered across diverse exposures, outcomes, and analytical frameworks. This study aimed to systematically organize published PCOS-related MR evidence and develop an interactive platform to support evidence retrieval, comparison,...

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PMID: 42629737
DOI: 10.1097/MD.0000000000050366
PMCID: PMC13502786

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