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Article

Genetic associations of metabolic factors and therapeutic drug targets with polycystic ovary syndrome.

Journal of advanced research - 1 Sept 2025

Zhang Changlong, Li Yuxuan, Wang Yang, Hu Shourui, Liu Yue, Liang Xiaofan, Chen Zi-Jiang, Zhang Yuqing, Zhao Han

Abstract excerpt

INTRODUCTION: Polycystic ovary syndrome (PCOS) is frequently accompanied with metabolic dysfunctions, yet the causal relationships between metabolic factors and PCOS remain to be conclusively established and etiology-based therapies are lacking. OBJECTIVES: To comprehensively identify the metabolic causal factors and potential drug targets for PCOS. METHODS: This genetic association study was conducted using...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39489338
DOI: 10.1016/j.jare.2024.10.038
PMCID: PMC12789731

Genes

LPL
PCSK9
TG

Provenance

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