PangyPlot: multi-scale interactive visualization of pangenome variation graphs.

doi:10.1093/bioinformatics/btag619

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Article

PangyPlot: multi-scale interactive visualization of pangenome variation graphs.

Bioinformatics (Oxford, England) - 3 Aug 2026

Mastromatteo Scott, Chirmade Shalvi, Roshandel Delnaz, Thiruvahindrapuram Bhooma, Wang Zhuozhi, Patel Rohan V, Sung Wilson W L, Hajianpour Amirhossein, Wang Cheng, Lin Fan, Keenan Katherine, Avolio Julie, Eckford Paul D W, Ratjen Felix, Strug Lisa J

Abstract excerpt

SUMMARY: Pangenome variation graphs integrate multiple samples into a unified representation, mitigating the reference bias inherent to linear genomes. However, these graphs can be large and structurally complex. Existing visualization tools are each confined to a fixed scale of resolution, requiring researchers to switch between multiple tools to examine variation at different levels of detail. PangyPlot is an...

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PMID: 42613741
DOI: 10.1093/bioinformatics/btag619
PMCID: PMC13523859

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