Article
Human Leukocyte Antigen Alleles (HLA-A, HLA-B, and HLA-DRB1) are associated with Acute Lymphoblastic Leukemia (ALL) : A Case-Control Study in a Sample of Iranian Population.
Asian Pacific journal of cancer prevention : APJCP - 1 May 2024
Kohansal Vajari Mahdi, Ehsan Mohsen, Ghiasi Saeedeh, Fooladi Saba, Karami Najibe, Hassanshahi Gholamhossein, Fatemi Ahmad
Abstract excerpt
OBJECTIVE: This study seeks to elucidate the association between HLA-A, HLA-B, and HLA-DRB1 alleles and their relative risk contributions to ALL within an Iranian cohort. METHODS: Utilizing a robust case-control design, this research involved 71 ALL patients and 71 age and sex-matched healthy individuals. Genotyping of specified HLA alleles was performed using the advanced PCR-SSP technique. RESULTS: Our findings...
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