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H3K27M and TERT promoter mutations are poor prognostic factors in surgical cases of adult thalamic high-grade glioma

1 Jan 2021

Abstract excerpt

Abstract Background Thalamic high-grade gliomas (HGGs) are rare tumors with a dismal prognosis. H3K27M and telomerase reverse transcriptase promoter (TERTp) mutations reportedly contribute to poor prognoses in HGG cases. We investigated the outcomes of surgically treated adult thalamic HGGs to evaluate the prognostic significance of H3K27M and TERTp mutations. Methods We retrospectively analyzed 25 adult patients...

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Glioma Diagnosis and Treatment
Meningioma and schwannoma management
Neurofibromatosis and Schwannoma Cases

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34013205
DOI: 10.1093/noajnl/vdab038

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