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Article

Genetic Ancestry and Colorectal Cancer in the All of Us Dataset.

JAMA network open - 3 Aug 2026

Chatzipanagiotou Odysseas P, Charalampous Charalampos M, Cordle Adam, Elemosho Abdulaziz, Alizai Qaidar, Mevawalla Areesh, Arena Lorenza, Ejaz Rida, Pawlik Timothy M

Abstract excerpt

Importance: Genetic ancestry may complement biological, behavioral, and clinical factors in understanding colorectal cancer (CRC) disparities; yet, ancestry-informed analyses in CRC remain limited. Objective: To characterize associations of genetic ancestry with CRC burden, age at diagnosis, and age-specific risk, and to develop a multiethnic CRC risk-prediction model. Design, Setting, and Participants: This...

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Aged
BRCA gene mutations in cancer
Colorectal Neoplasms
Ethnicity
Genetic Associations and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

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PMID: 42584889
DOI: 10.1001/jamanetworkopen.2026.28789
PMCID: PMC13470293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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