Article
Integrating GlycoSHIELD Modeling and DNA-PAINT SMLM to Map the Glycosylation-Dependent Distribution of the Na,K-ATPase.
The Journal of membrane biology - 12 Aug 2026
Stojcic Bruno, Draczkowski Piotr, Patrick Joan, Saeed Mezida, Brismar Hjalmar
Abstract excerpt
The cell surface localization of the Na,K-ATPase (sodium pump) is required for maintaining transmembrane electrochemical gradients. While glycosylation of the β1 subunit facilitates trafficking from the endoplasmic reticulum to the plasma membrane, its role in nanoscale surface organization is not characterized. This study employed GlycoSHIELD computational modeling and DNA-PAINT single-molecule localization...
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