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Article

Proteomic Mediators of Chronic Obstructive Pulmonary Disease Phenotypes and Coronary Artery Calcification Burden in Ever Smokers.

Journal of the American Heart Association - 18 Aug 2026

Abbasi Asghar, Ahmad Khadije, Pratte Katherine A, Moore Jeff, DeMeo Dawn L, Manubolu Venkat S, Kinninger April, Tiller Nicholas B, Bowler Russell P, Budoff Mathew, Casaburi Richard, Rossiter Harry B

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) increases cardiovascular disease risk. Coronary artery calcification (CAC) predicts cardiovascular events and mortality in COPD. We hypothesized that plasma proteins linked to pulmonary phenotypes mediate CAC burden. METHODS: Pulmonary function, emphysema, airway wall thickening, Agatston CAC scores (inverse normal transformed), and relative abundance of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42568067
DOI: 10.1161/JAHA.125.046201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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