Article
The association of plasma biomarkers with computed tomography-assessed emphysema phenotypes.
Respiratory research - 12 Oct 2014
Carolan Brendan J, Hughes Grant, Morrow Jarrett, Hersh Craig P, O'Neal Wanda K, Rennard Stephen, Pillai Sreekumar G, Belloni Paula, Cockayne Debra A, Comellas Alejandro P, Han Meilan, Zemans Rachel L, Kechris Katerina, Bowler Russell P
Abstract excerpt
RATIONALE: Chronic obstructive pulmonary disease (COPD) is a phenotypically heterogeneous disease. In COPD, the presence of emphysema is associated with increased mortality and risk of lung cancer. High resolution computed tomography (HRCT) scans are useful in quantifying emphysema but are associated with radiation exposure and high incidence of false positive findings (i.e., nodules). Using a comprehensive...
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